advanced cell culture

Advanced cell culture system  is developped  for long-term culture and differentiation of human induced pluripotent stem cells (hiSPCs). It is designed for in-vivo mimicking  of nutrient feeding in a perfusion-diffusion regime. It allows reducing time and laborious efforts as well as risks of contamination. Typically, it is composed of  different separate units to control cell culture medium with selected factors injection and distribution. The system could also be placed in an incubator. Depending on applications, different configurations could be realized.  The whole processes can then be programmed with minimum human intervention with good cell culture reproducibility.  It can also be combined with other fluidic element, allowing automated cell sorting, labeling, sample preparing, etc. The system is applicable to both dish , organ chip based assays developed by MesoBioTech. 

models

ac-121

AC-121  is an integrated system allowing auto feeding  and recycling with one culture medium to one dish.

ac-126

AC-121  is an integrated system allowing auto feeding  and recycling with one culture medium up to six dish.

ac-621

AC-621  is an integrated system allowing auto distribution up to 6 factors  to  one culture dish.

main features

specifications

Configurations& parameters

 Peristaltic pump:   0-300rmp/min

 Rotary valve: 8 channels, response time 1s

 Flow speed:  3ul/min-40ml/min

 Interface communication: RS485

General parameters

Gas fittings: Luer

Dimensions: 155 × 175 × 100 mm

Weight: 1Kg

applications

Mature neuron generation

Immunofluorescence images of mature neurons after differentiation for 78 days by manual and automated method

cardiac tissue formation

Microscopy images of mature cardiac tissue sheets after differentiation for 20 days by advanced cell culture system