Integrated chips are manufactured by mass production. The basic element of the chip (upper part) is a plastic plate with standard Luer connectors and an elastomeric thin film for conformal contact with the lower part in which microfluidic circuits can be patterned. While the lower part can be a sheet in plastic, elastomeric, glass, silicon or other materials, standard elements such as mixing Y-channels, gradient Xmas trees, droplet generators, etc. can be patterned. The upper and the lower part of the chip can be reversely or irreversibly assembled.
With a simple mechanic clamp, good sealing is achievable. Otherwise, MesoBioTech offers irreversibly assembled devices for common uses.